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Multi-Bioactive Mela-Prep Lotion contains a combination of highly specialized ingredients, including Sepi-White MSH, Niacinamide PC, and Alpha-Arbutin that scientific studies show to assist in blocking the effects of Tyrosinase, reducing the effects of melanin transfer to keratinocytes, resulting in an improved appearance of uneven skin tone, leaving the skin looking brighter and more even-toned.


SEPI-WHITE-MSH™ (Undecylenoil Phenylalanine) Sepi-White-MSH™ is a MSH receptor antagonist, and has been shown to reduce melanin production by blocking the cell’s biological response to produce pigment.

ALPHA-ARBUTIN has an impressive ability to inhibit the over production of tyrosinase, an enzyme which causes pigmentation.

NIACINAMIDE (Vitamin B3) inhibits the transfer of melanin into the keratinocyte (skin cell). Niacinamide also reduces inflammation, which causes pigment production, by improving the skin’s barrier function and stimulating ceramide production.

Aqua (Water), Pentylene Glycol, Niacinamide, Alcohol Denat., Undecylenoyl Phenylalanine, Alpha-Arbutin, Tromethamine, Ethylhexylglycerin, Hydroxypropyl Guar, Disodium EDTA, Sodium Phosphate, Tocopherol, Sodium Hydroxide, Phenoxyethanol

Recommended Use

Cleanse skin, or splash with water if not using a cleanser, tone if desired. If you are using Multi-Bioactive Mela-Prep Lotion for the first time begin by applying a thin layer of lotion to the areas with the darkest pigment, morning and night, for two weeks. This allows the heaviest pigment to get a “head start” on the lightening process. After two weeks, use by applying a thin layer of lotion to your face, neck and chest (also great for your hands), morning and night, followed by any desired serums, moisturizers or oils.

For optimal pigmentation improvement, we recommend using Multi-Bioactive Mela-Prep Lotion in conjunction with Vita-Botanical Mela-Fade Serum System A + B.

Multi-Bioactive Mela-Prep Lotion helps improve pigmentation caused by sun and environmental damage; we recommend wearing sunscreen everyday to preserve any improvements and keep skin cells safe and healthy.